CCRIS 8650
Azelnidipine
CAS: 123524-52-7
Molecular Formula: C33H34N4O6
CCRIS 8650 - Names and Identifiers
CCRIS 8650 - Physico-chemical Properties
| Molecular Formula | C33H34N4O6 |
| Molar Mass | 582.65 |
| Density | 1.33±0.1 g/cm3(Predicted) |
| Melting Point | 120-126°C |
| Boling Point | 709.3±60.0 °C(Predicted) |
| Flash Point | 382.8°C |
| Solubility | DMSO: >10mg/mL |
| Vapor Presure | 5.74E-20mmHg at 25°C |
| Appearance | powder |
| Color | Yellow |
| Merck | 14,907 |
| pKa | 7.89(at 25℃) |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Refractive Index | 1.658 |
| MDL | MFCD00865803 |
| Use | Azelnidipine is a dihydropyridine calcium channel blocker. |
| In vitro study | Azelnidipine is a newly developed long-acting calcium channel blocker with unique pharmacological properties, such as slowing the heartbeat and high affinity for vascular tissue, these properties make it different from other calcium channel blockers, so Azelnidipine is a new generation of calcium channel blockers that can be used to treat high blood pressure, regardless of whether the patient is at risk of ischemic heart disease. Because of its high fat solubility, it can still remain in the blood vessel wall after it is cleared from the blood. |
CCRIS 8650 - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R22 - Harmful if swallowed R41 - Risk of serious damage to eyes |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 - Wear eye / face protection. |
| WGK Germany | 3 |
| RTECS | US7968332 |
| Toxicity | LD50 in female, male mice, female, male rats (mg/kg): 785, 979, 1267, 1971 orally |
CCRIS 8650 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 1.716 ml | 8.581 ml | 17.163 ml |
| 5 mM | 0.343 ml | 1.716 ml | 3.433 ml |
| 10 mM | 0.172 ml | 0.858 ml | 1.716 ml |
| 5 mM | 0.034 ml | 0.172 ml | 0.343 ml |
Last Update：2024-01-02 23:10:35
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View History
CCRIS 8650
2-(4-甲氧苯基)四氢呋喃
3-氟吡啶-4-硼酸 (含有数量不等的酸酐)
甲基碳化异氰碘酯
VargatefTM BIBF
CCRIS 3128
氯甲基乙基二甲基硅烷
D-半胱氨酸盐酸盐 D-半胱氨酸盐酸盐一水合物
2-(4-甲氧苯基)四氢呋喃
3-氟吡啶-4-硼酸 (含有数量不等的酸酐)
甲基碳化异氰碘酯
VargatefTM BIBF
CCRIS 3128
氯甲基乙基二甲基硅烷
D-半胱氨酸盐酸盐 D-半胱氨酸盐酸盐一水合物